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Rabbit Anti-Human URI1 monoclonal antibody, clone TQ326

Rabbit Anti-Human URI1 monoclonal antibody, clone TQ326

Cat no: CABT-L1880

Supplier: Creative Diagnostics
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Rabbit Anti-Human URI1 monoclonal antibody for IHC-P, FC. Unconventional prefoldin RPB5 interactor (URI) is an oncogene required for the survival of some human carcinomas and is often amplified and over-expressed in subsets of carcinomas from ovary, breast, stomach, and lung. Activation of URI contributes an important mechanism for activating mitochondrial S6K1-BAD signaling and promoting cell survival through disabling PP1?-dependent negative feedback inhibition. URI can negatively modulate RNA polymerase II subunit 5 (RPB5) and mediates resistance of cells to cisplatin.
Catalogue number: CABT-L1880
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TQ326
Gene: 8725
Target: URI1
Isotype: IgG
Clonality: Monoclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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