Home  >  Products  >  Rabbit Anti-Human ZAP70 (phospho Tyr315, Tyr319) monoclonal antibody, clone 5I27M20
Rabbit Anti-Human ZAP70 (phospho Tyr315, Tyr319) monoclonal antibody, clone 5I27M20

Rabbit Anti-Human ZAP70 (phospho Tyr315, Tyr319) monoclonal antibody, clone 5I27M20

Cat no: CABT-L1662

Supplier: Creative Diagnostics
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Rabbit Anti-Human ZAP70 (phospho Tyr315, Tyr319) monoclonal antibody for FC, ICC, IF, WB. Zeta-associated protein (ZAP-70), a 70 kDa member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Upon T-cell antigen receptor. Phosphorylation of both tyrosines 315. Phosphorylation of tyrosines 315 and 319 plays an important role in mediating the positive and negative selection of T cells in thymus. TLR9-activated B-cells display elevated ZAP-70 expression levels which correlate with sustained PKB induction. Additionally,, a major catechin found in green tea, binds directly to ZAP-70 resulting in caspase-mediated apoptosis in Jurkat cells.
Catalogue number: CABT-L1662
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 5I27M20
Target: ZAP70
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
Creative Diagnostics
Get a Quote Direct from
Creative Diagnostics

By submitting this form you agree to your details being passed to Creative Diagnostics for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave