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Rabbit Anti-Mouse GZMD Polyclonal antibody

Cat no: CABT-L2322

Rabbit Anti-Mouse GZMD Polyclonal antibody

Rabbit Anti-Mouse GZMD Polyclonal antibody for WB. Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.; The granzyme d enzyme is thought to be necessary for target cell lysis in cell-mediated immune responses.

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SPECIFICATIONS

Catalog Number

CABT-L2322

Hosts

Rabbit

Reactivities

Mouse

Conjugates

Unconj

Target

GZMD

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Avoid repeated freeze/thaw cycles. Store at 4В°C for frequent use. Aliquot and store at -20В°C for 12 months.

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