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Rabbit Anti-Mouse GZMD Polyclonal antibody

Cat no: CABT-L2322


Supplier: Creative Diagnostics
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Rabbit Anti-Mouse GZMD Polyclonal antibody for WB. Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.; The granzyme d enzyme is thought to be necessary for target cell lysis in cell-mediated immune responses.
Catalogue number: CABT-L2322
Reactivities: Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Target: GZMD
Isotype: IgG
Clonality: Polyclonal
Storage temp: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.

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