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Products Sphingosine Kinase 1 Polyclonal Antibody
| Catalogue number: | 10006822 |
| Hosts: | Rabbit |
| Applications: | Immunocytochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | human sphingosine kinase 1 (SPHK 1) amino acids 264-274 (DLESEKYRRLG) |
| P type: | Antibodies|Ceramides/Sphingolipids|Lipids|Protein Kinase|Intracellular Signaling |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | SPHK 1 catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate. This reaction plays an important role in determining cell proliferation versus cell death. SPHK 1 is found in a wide variety of tissues and cell types including kidney, liver, spleen, heart, platelets, and human tumors. On a cellular level, it is found in the cytosolic and membrane fractions. Based on the amino acid sequence, this protein has a molecular weight of approximately 43 kDa. The observed band at 50 kDa may be explained by some reported post translational modifications. |
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