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Thioguanine (2C2) Antibody

Thioguanine (2C2) Antibody

Cat no: 250360


Supplier: ABBIOTEC
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Thioguanine is a purine analogue used in cancer chemotherapy. It is the 6-thione analogue of the endogenous 6-OH purine base guanine. In the cell thioguanine is converted to the ribonucleotides: 6-thioguanosine-5'-phosphate and 6-thioinosine-5'-phosphate. These fraudulent nucleotides produce their cytoto, Xenopus/Amphibian,ic effects by several mechanisms, e.g. inhibitory action on de novo purine synthesis, and may themselves be incorporated into DNA. Thioguanine has a molecular weight of 167 Da. This antibody is specific for thioguanine. Cross-reactivity is seen with 6-(methylthio)purine, but not with various other thioguanine analogs.
Catalogue number: 250360
Size: 0.2 mg
Accession: P00492
Antigen: S-substituted thioguanine linked to PPD (2)
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG2a/l
Clonality: 2C2
Additional info: HGPRT; HGPRTase
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