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Tollip (W151) Peptide

Tollip (W151) Peptide

Cat no: BS9228P

Supplier: Bioworld Technology, Inc.
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Tollip (toll-interacting protein) serves as a suppressor of innate immunity signaling and links the serine/threonine kinase IRAK to the IL-1 receptor complex upon receptor activation. Overexpression of Tollip in HEK-293 cells inhibits NFkB activation in response to TLR2 and TLR4 signaling. Negative regulation of TLR signaling by Tollip may limit the production of proinflammatory mediators during inflammation and infection. Tollip forms a complex with Tom1 to regulate endosomal trafficking of ubiquitinated proteins. The Tollip protein shows ubiquitous expression in mouse.
Catalogue number: BS9228P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9H0E2
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Tollip (W151). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Adapter protein; FLJ33531; IL 1RAcPIP; IL1RAcPIP; TOLIP; TOLIP; Toll interacting protein; Toll-interacting protein; tollip
Additional info: This peptide can be used with studies using BS9228 Tollip (W151) pAb.

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