Home  >  Products  >  TRAP, Recombinant, Murine (CD40-L, Tumor necrosis factor ligand superfamily member 5, TNF-related activation protein, TRAP, T cell antigen Gp39, CD154 antigen, sCD40, IGM, IMD3, HIGM1, T-BAM, TNFSF5, hCD40L, CD40 ligand, CD40-L, Tumor necrosis factor liga

TRAP, Recombinant, Murine (CD40-L, Tumor necrosis factor ligand superfamily member 5, TNF-related activation protein, TRAP, T cell antigen Gp39, CD154 antigen, sCD40, IGM, IMD3, HIGM1, T-BAM, TNFSF5, hCD40L, CD40 ligand, CD40-L, Tumor necrosis factor liga

Cat no: 167983


Supplier: United States Biological
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CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18kD soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant murine CD40 Ligand is a soluble 18kD protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L. Source: Recombinant protein corresponding to mouse CD40Ligand/TRAP, expressed in E. coli. Molecular Weight: ~16.4kD Biological Activity: ED50 is <0.1ug/ml determined by its ability to induce TNF-a and MIP-1a production by murine splenocytes. Endotoxin: <0.1ng/ug Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 167983
Size: 25ug
Form: Supplied as a lyophilized powder in 10mM sodium phosphate, pH 7.5, 0.1M arginine. Reconstitute in ddH2O to a concentration of 0.1-1.0mg/ml.
Purity: ~98% (SDS-PAGE, HPLC)

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