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Tubulin beta 1 pAb

Tubulin beta 1 pAb

Cat no: AP0065


Supplier: Bioworld Technology, Inc.
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Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain .Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally.
Catalogue number: AP0065
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q9H4B7
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human Tubulin beta 1.
Species: Tubulin beta 1 pAb detects endogenous levels of Tubulin beta 1 protein.
Molecular weight: ~ 50 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha tubulin; Alpha-tubulin ubiquitous; Beta 5 tubulin; Beta tubulin; DAQB 47P19.9 001; dJ40E16.7; K alpha 1; K alpha 1 protein; M40; MGC117247; MGC16435; OK/SW cl.56; TBA1B; TUBA1; TUBA1B; TUBB 1; TUBB 2; TUBB 3; TUBB 4; TUBB 5; TUBB; TUBB protein; TUBB1; TUBB2; TUBB2A; TUBB2C; TUBB3; TUBB4; TUBB5; Tubulin alpha-1B chain; Tubulin alpha-ubiquitous chain; Tubulin beta 1b; Tubulin beta 2 chain; Tubulin beta 2A; Tubulin beta; Tubulin beta polypeptide; Tubulin K-alpha-1; XXbac BCX111D4.2 001;
Additional info: For research use only, not for use in diagnostic procedure.

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