JAM2, NT (JAM2, C21orf43, VEJAM, Junctional adhesion molecule B, Junctional adhesion molecule 2, Vascular endothelial junction-associated molecule, CD322) (APC)

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

037183-APC

Size

200ul

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)\nUeki, T., et al. Microvasc. Res. 75(2):269-278(2008)\nWeber, C., et al. Nat. Rev. Immunol. 7(6):467-477(2007)\nLiu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)\nZhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)

Additional Info

Human

Alternative Names

JAM2, C21orf43, VEJAM, Junctional adhesion molecule B, Junctional adhesion molecule 2, Vascular endothelial junction-associated molecule, CD322