Suppliers Cayman Chemical Company
Cayman's LTC4 Assay is a competitive EIA that can best be used for the quantification of LTC4 in select sample types. Cultured cells synthesizing LTC4 will...
LTB4 is synthesized from arachidonic acid by the combined action of 5-LO and LTA4 hydrolase. LTB4 has long been recognized as a potent mediator of...
Thromboxane A2 (TXA2), produced from arachidonic acid, causes irreversible platelet aggregation, vascular, and bronchial smooth muscle contraction. TXA2 is...
17-phenyl trinor PGF2(alpha) is a metabolically stable analog of PGF2(alpha) and is a potent agonist for the FP receptor. The ethyl amide analog has been...
Latanoprost is an F-series PG analog which has been approved for use as an ocular hypotensive drug. PG esters and other similar derivatives act as prodrugs...
Fluprostenol is a metabolically stable analog of PGF2(alpha) with potent FP receptor agonist activity. The isopropyl ester of fluprostenol has been approved...
PGF2(alpha) is rapidly metabolized to 13,14-dihydro-15-keto PGF2(alpha) in vivo, by the enzymes 15-hydroxy PG dehydrogenase and D13-reductase. Measurement of...
11(beta)-PGF2(alpha) is the primary plasma metabolite of PGD2 in vivo, the levels of which can increase from 6 pg/ml in a normal healthy volunteer to 490...
This assay offers the convenience of a fast assay (2 hour incubation; 1 hour development) while still achieving a detection limit (80% B/B0) of 10 pg/ml.
The isoprostanes are a family of eicosanoids of non-enzymatic origin produced by the random oxidation of tissue phospholipids by oxygen radicals....
PGF2(alpha) is one of the five primary PGs derived enzymatically directly from the endoperoxide PGH2. The majority of the functional roles ascribed to it...
Prostacyclin is formed from arachidonic acid primarily by the vascular endothelium and renal cortex. It is a potent vasodilator and inhibitor of platelet...
Because of the rapid metabolism of PGE2, the determination of in vivo PGE2 biosynthesis is often best accomplished by the measurement of PGE2 metabolites....
This assay was developed for screening applications in which the relative amount of PG production for a large number of cell culture samples must be...
Cayman's PGE2 EIA is a sensitive competitive assay that uses a high-affinity PGE2 monoclonal antibody for quantification of PGE2 in plasma, urine, and...
Prostaglandin D2 (PGD2) is biosynthesized in the brain by soluble, glutathione-independent lipocalin-type PGD2 synthase. PGD2 accumulates in the...
Prostaglandin D2 (PGD2) is biosynthesized in the brain by a soluble, 26 kDa glutathione-independent lipocalin-type PGD2 synthase. This PGD2 accumulates in...
This PGD2-MOX EIA is based on the conversion of PGD2 to a stable MOX derivative. Treatment of the sample with MOX HCl converts PGD2 into PGD2-MOX, preventing...
The primary synthesis of functional vitamin D begins in the skin, where a cholesterol by-product acted upon by UV light forms vitamin D3. Vitamin D3 is...
Interleukin-6 (IL-6) is produced by multiple cell types, including monocytes, macrophages, and T cells and is involved in many defense mechanisms including...
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