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United States Biological

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Milrinone (1, 6- dihydro- 2- methyl- 6- oxo- [3, 4'- bipyridine]- 5- carbonitrile, WIN 47, 203)
Milrinone (1, 6- dihydro- 2- methyl- 6- oxo- [3, 4'- bipyridine]- 5- carbonitrile, WIN 47, 203)
United States Biological

Cell-permeable. A potent, cAMP-specific phosphodiesterase (PDEIII ) inhibitor (IC?? = 0.45 and 1.0um for PDEIIIA and PDEIIIB, respectively). It inhibits...

MIF antagonist, p425 (Chicago Sky blue 6B, 6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonic acid] tetrasodium salt)
MIF antagonist, p425 (Chicago Sky blue 6B, 6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonic acid] tetrasodium salt)
United States Biological

A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. Acts as an allosteric MIF (macrophage migration...

Membrane Protein Extraction BioAssay(TM) Kit
Membrane Protein Extraction BioAssay(TM) Kit
United States Biological

The Membrane Protein Extraction BioAssay(TM) Kit provides optimized buffers and reagents for effective extraction of membrane proteins from mammalian tissues...

MAPKAPK3, Active, Recombinant, Human (Active MAPKAPK3, MAPKAPK3, MAPKAPK, human MAPKAPK3, active kinase, active kinases, recombinant MAPKAPK3, recombinant MAPKAPK3 kinase activity assay, protein kinase)
MAPKAPK3, Active, Recombinant, Human (Active MAPKAPK3, MAPKAPK3, MAPKAPK, human MAPKAPK3, active kinase, active kinases, recombinant MAPKAPK3, recombinant MAPKAPK3 kinase activity assay, protein kinase)
United States Biological

MAPKAPK3 has a single potential SH3-binding site in the proline-rich N terminus, a putative ATP-binding site, 2 MAP kinase phosphorylation site motifs, and a...

MAPKAPK-2, Control Peptide
MAPKAPK-2, Control Peptide
United States Biological

blocking peptide for M2355-02A. Source: Synthetic peptide corresponding to MAPKAPK-2. Applications: Suitable for use in ELISA and Antibody Blocking. Other...

LY-333,531 hydrochloride (Ruboxistaurin)
LY-333,531 hydrochloride (Ruboxistaurin)
United States Biological

An isozyme-selective inhibitor of protein kinase Cb (PKCb). Inhibits both the PKCbI (IC??=4.7 nM) and PKCbII (IC??=5.9nm) isozymes. LY-333,531 is 76- and...

Long R3 IGF-I, Recombinant, Human, (Human IGF-I, IGF-I, IGFI, IGF I, h-IGF-I, rh-IGF-I, recombinant human IGF-I, recombinant IGF-I, IGF-I, Long R3, Long R3 IGF-I)
Long R3 IGF-I, Recombinant, Human, (Human IGF-I, IGF-I, IGFI, IGF I, h-IGF-I, rh-IGF-I, recombinant human IGF-I, recombinant IGF-I, IGF-I, Long R3, Long R3 IGF-I)
United States Biological

IGF-I (insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone,...

Lithocholic acid (3alpha-Hydroxy-5beta-cholan-24-oic acid, 3alpha-Hydroxy-5beta-cholanic acid, 5beta-Cholan-24-oic acid-3alpha-ol, LCA)
Lithocholic acid (3alpha-Hydroxy-5beta-cholan-24-oic acid, 3alpha-Hydroxy-5beta-cholanic acid, 5beta-Cholan-24-oic acid-3alpha-ol, LCA)
United States Biological

Lithocholic acid (LCA) is a hydrophobic secondary bile acid that acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic...

Lipid Peroxidation (MDA) BioAssay(TM) Kit (Colorimetric, Fluorometric)
Lipid Peroxidation (MDA) BioAssay(TM) Kit (Colorimetric, Fluorometric)
United States Biological

Quantification of lipid peroxidation is essential to assess oxidative stress in pathophysiological processes. Lipid peroxidation forms Malondialdehyde (MDA)...

Lipase Activity BioAssay(TM) Kit III (Fluorometric)
Lipase Activity BioAssay(TM) Kit III (Fluorometric)
United States Biological

Lipase is a subclass of the esterases that catalyze the hydrolysis of ester bonds of lipid substrates. Lipases perform essential roles in the digestion,...

LDH Cytotoxicity BioAssay(TM) Kit II (Colorimetric)
LDH Cytotoxicity BioAssay(TM) Kit II (Colorimetric)
United States Biological

Cell death or cytotoxicity is classically evaluated by the quantification of plasma membrane damage. Lactate dehydragenase (LDH) is a stable enzyme, present...

KT5823 (2, 3, 9, 10, 11, 12- hexahydro- 10R- methoxy- 2, 9- dimethyl- 1- oxo- 9S, 12R- epoxy- 1H- diindolo[1, 2, 3- fg:3
KT5823 (2, 3, 9, 10, 11, 12- hexahydro- 10R- methoxy- 2, 9- dimethyl- 1- oxo- 9S, 12R- epoxy- 1H- diindolo[1, 2, 3- fg:3
United States Biological

Cell-permeable. KT5823 is a derivative of K-252a that acts as a selective inhibitor of Protein kinase G (PKG) (Ki = 0.234um). Inhibits other kinases at much...

KLK3, Recombinant, Human (Kallikrein-3, APS, KLK2A1, PSA, Hk3)
KLK3, Recombinant, Human (Kallikrein-3, APS, KLK2A1, PSA, Hk3)
United States Biological

Prostate-specific antigen, also known as Gamma-seminoprotein, Kallikrein-3, kallikrein-related peptidase 3, Semenogelase, KLK3 and PSA, is a secreted protein...

JNK Kinase Activity Screening BioAssay(TM) Kit
JNK Kinase Activity Screening BioAssay(TM) Kit
United States Biological

c-Jun N-terminal kinase (JNK) is one of the several main MAP kinase groups identified in mammals. Recent evidences suggest that activation of JNK may play an...

JNK Kinase Activity BioAssay(TM) Kit
JNK Kinase Activity BioAssay(TM) Kit
United States Biological

c-Jun N-terminal kinase (JNK) is one of the several main MAP kinase groups identified in mammals. Recent evidences suggest that activation of JNK may play an...

IWP-2 (N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide)
IWP-2 (N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide)
United States Biological

Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50 = 27nM) by inhibition of the O-acyltransferase...

ITSA-1 (N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide, ITSA1)
ITSA-1 (N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide, ITSA1)
United States Biological

Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone...

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