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Desmogleins (dsgs) are type I membrane proteins that are important for cell adhesion and are expressed in great abundance at the desmosomes, which are...
The multigene family of Fc receptor homologs (FcRHs,CD307) have variable numbers of extracellular immunoglobulin domains of five different subtypes. FcRH...
CD300LF (CD300 molecule-like family member f), also known as NKIR (NK inhibitory receptor), IREM1 (immune receptor expressed on myeloid cells 1), CLM1...
B and T lymphocyte attenuator (BTLA,CD272) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T cell activation. BTLA is...
DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor)...
HA effects are mediated through two receptors, CD44 (also designated HCAM) and the receptor of hyaluronic acid mediated motility (RHAMM). RHAMM, also...
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also...
Syndecan-1 (SYND1), also designated CD138, is a type I integral membrane proteoglycan that contains both chondroitin sulfate and heparan sulfate groups. It...
LAMP-1 (also designated CD107a) and LAMP-2 (also designated CD107b) are involved in a variety of functions, including cellular adhesion, and are thought to...
CD92, also known as SLC44A1 (solute carrier family 44, member 1), CDw92 or CTL1 (choline transporter-like protein 1), is a 657 amino acid multi-pass membrane...
Thy1 is a GPI-anchored, developmentally regulated protein involved in various signaling cascades that mediate neurite outgrowth, T cell activation, tumor...
CD32 (also designated Fcgamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes...
CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of...
Helicase with RNase motif, more commonly designated Dicer, cleaves doublestranded RNA (dsRNA) in the RNA interference and small temporal RNA (stRNA)...
All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile...
The vaccinia-related kinase (VRK) proteins consist of three Ser-Thr kinases, designated VRK1, VRK2 and VRK3. In the human kinome, VKR proteins function as...
TESK2 (testicular protein kinase 2) is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning...
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII...
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular...
Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host...
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