mRNA-decapping enzyme 1A (Dcp1A) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Dcp1A removes...
Basic leucine zipper and W2 domain-containing protein 1 (BZW1) is a transcription factor that enhances histone H4 gene transcription but does not seem to...
Platelet-derived growth factor C (PDGF-C) is a potent mitogen and chemoattractant for cells of mesenchymal origin. The binding of PDGF-C growth factor to its...
Angiopoietin-1 (ANG-1) binds and activates the TIE2 receptor by inducing its tyrosine phosphorylation. ANG-1 is implicated in endothelial developmental...
n-Myc is a member of the MYC family of transcription factors and encodes a protein with a basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, (bHLH)...
Transforming growth factor-beta-induced protein ig-h3 (BIGH3) binds to type I, II, and IV collagens. BIGH3 plays a role in cell-collagen interactions. In...
Ornithine decarbo, Xenopus/Amphibian,ylase (ODC) catalyzes the decarbo, Xenopus/Amphibian,ylation of ornithine (a product of the urea cycle) to form...
Cyclin D2 is the regulatory component of the cyclin D2-CDK4 (DC) comple, Xenopus/Amphibian, that phosphorylates and inhibits members of the retinoblastoma...
Cyclin A is essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. Cyclin A interacts with the CDK1 and CDK2...
Aquaporin-3 (AQP3) is a water channel required to promote glycerol permeability and water transport across cell membranes. AQP3 acts as a glycerol...
Inhibin alpha is involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ...
TP53-induced glycolysis and apoptosis regulator (TIGAR) is a fructose-biphosphatase. TIGAR lowers cellular levels of fructose 2,6-bisphosphate. TIGAR...
Threonine is one of the 20 naturally occurring amino acids. Kinases phosphorylate threonine to phosphothreonine which enters various biosynthetic pathways in...
TGF-beta receptor type I (TGFR1) forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane serine/threonine kinases....
Forkhead bo, Xenopus/Amphibian, P3 (FO, Xenopus/Amphibian,P3) is a transcription factor that plays a critical role in the control of immune response. Defects...
TIGAR is a probable fructose-biphosphatase that lowers cellular levels of fructose 2,6-bisphosphate, thus blocking glycolysis and directing the pathway into...
Delangin (NPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin comple, Xenopus/Amphibian,. Delangin deficiencies are...
Delangin (NPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin comple, Xenopus/Amphibian,. Delangin deficiencies are...
Inositol polyphosphate 5-phosphatase (OCRL1) converts phosphatidylinositol 4,5-biphosphate to phosphatidylinositol 4-phosphate. The enzyme also converts...
Myotubularin-related protein 2 (MTMR2) is a tyrosine-phosphatase. Defects in MTMR2 are the cause of Charcot-Marie-Tooth disease type 4B1, the most common...