Drug Discovery
The drug discovery and development process has traditionally taken 12 to 15 years to identify a potential target and molecule in the lab; synthesize and screen the molecule; test the molecule in vitro and in humans; perform clinical trials; obtain regulatory approval (Pharmacopeia, GLP and/or ISO); develop and scale-up manufacturing processes; and begin commercial production and shipping.
Because of the extended time to market and expense of developing new drugs, the pharmaceutical business is focusing on more disruptive discoveries, such as curing an incurable disease or preventing a disease, rather than just developing new drugs that produce only slight improvements. New paradigms in drug discovery are evolving to reduce development time and expense by networking multi-functional teams which are patient-focused.
Laboratory instruments for drug discovery include protein interaction array systems; gamma counters; HPLC systems; microplate luminometers and fluorometers; mass spectrometers; microarray scanners; hybridization reaction stations; and modular plant imaging systems.
Equipment, consumables and services for drug discovery labs include transfection reagents; cDNA and RNA synthesis kits; assay and ELISA kits; melting point apparatuses; microplate washers; cryogenic freezers; cryogenic tubes; ergonomic and multichannel pipettes and pipette tip racks and refills; pluripotent stem cells; reaction plates and modules; tumor tissue with matched blood samples; custom protein production in E. coli; injection services; DNA sequencing services; tissue homogenizers; and biobanking software.
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