Categories Drug Discovery
Small molecule drugs play a very important role in the treatment of diseases, and their mechanism of action is to exert their function by interacting with...
Recombinant protein drugs are produced using recombinant DNA or RNA technologies. This involves the integration of target protein genes into recombinant...
Structural biology is a field grounded in molecular biology, biochemistry, and biophysics, focusing on the detailed study of biomacromolecules such as...
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is a mass spectrometry (MS) technique that studies protein spatial conformation. In this process,...
Proteins play a pivotal role in the regulation, function, and structure of various human organs and tissues. The regulation of the synthesis and degradation...
Tumor immunotherapy utilizes active or passive methods to provoke tumor-specific immune responses in the body, harnessing their inhibitory and cytotoxic...
Small molecules predominantly modulate the activity of their protein targets. The majority of approved small molecule inhibitors target intracellular...
Drug screening refers to the evaluated process of substances (samples) potentially used as drugs, assessing their biological activity, pharmacological...
Active Pharmaceutical Ingredients (APIs) are substances or mixtures employed in the production of drugs. They have pharmacological effects or directly...
Metal content analysis is a technique for detecting and quantifying concentration of metal elements in samples, crucial for ensuring the efficacy and safety...
The analysis of protein content in bioproducts is a principal method for assessing bioproduct quality and constitutes a significant aspect of bioproduct...
HCP antibody coverage refers to the proportion of specific host cell proteins (HCPs) detected by antibodies during pharmaceutical production. HCPs are...
MtoZ Biolabs uses 2D DIGE and Western blot technology for HCP analysis.
Glycosylation is a very important type of protein post-translational modification (PTM). It is estimated that over half of eukaryotic proteins undergo...
Proteins are ampholytes that contain both positively and negatively charged functional groups. Their net charge is predominantly determined by the pH of the...
As the pharmaceutical industry evolves, biopharmaceutical characterization has gradually become a hot research within the pharmaceutical sector....
Mass spectrometry N-terminal sequence analysis is a method that utilizes mass spectrometry technology to efficiently and accurately determine the amino acid...
The analysis of protein full sequence is a critical and challenging endeavor, especially against the backdrop of rapid advancements in the biopharmaceutical...
The C-terminal sequence is a pivotal structural and functional part of proteins and peptides, which may contain significant antigenic determinants (i.e.,...
The N-terminal sequence significantly influences a protein's half-life and its subcellular localization. This region is pivotal for the structural and...
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