Neurobiology
The study of neurobiology helps scientists understand the molecular, cellular, anatomical and physiological foundations of the way organisms see, feel, taste, smell, think, act, move, learn and develop over their lifetimes. All these are mediated by specialized communication cells called neurons, the majority of which are located in the brain and spinal cord.
One important focus of neurobiology is the study of how neurons transmit and receive electrical and chemical signals through bioelectrical circuits. In addition, clinical neurobiologists seek to understand and reverse pathologies of the central and peripheral nervous systems that cause stroke, epilepsy, Alzheimer’s disease and peripheral neuropathy.
Specialized laboratory instrumentation and supplies for neurobiology include an orofacial stimulation test for rats, which measures hypersensitivity to thermal or mechanical stimulation; an HD microimaging system for microsurgical and micro-dissection applications; custom monoclonal antibodies for neuroscience applications; specialty neuroscience chemicals; neural stem and progenitor cell assays; a synthetic retinoid derivative (EC23) culture supplement to enhance in vitro neuronal differentiation; and a novel tissue clearing reagent and microscope objective lens system that allows imaging of structures, such as neurons, extending up to 8 mm deep into tissues.
Other laboratory equipment and consumables for neurobiology include deep petri dishes; 3D tissue culture trays and scaffolding well inserts; mounting media; targeted toxins to develop cell "knockouts" with molecular neurosurgery; cytotoxicity and other assay kits; micropolymer detection reagents; conjugation kits; tissue homogenizers; centrifuges; freezers; incubators; shakers; biological safety cabinets; microscopes; flow cytometry systems; transcription kits and reverse transcriptase; blocking solution; cell membrane stabilizers; and cell lysing kits.
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