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1-(3-Chlorophenyl)piperazine-d8

Cat no: 006598


Supplier: United States Biological
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It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone. Form: Sticky Yellow Oil Solubility: Chloroform, Methanol
Catalogue number: 006598
Size: 1mg
Form: Sticky Yellow Oil
Alternative names: 1-(m-Chlorophenyl)piperazine-d8; 4-(3-Chlorophenyl)piperazine-d8; N-(3-Chlorophenyl)piperazine-d8; N-(m-Chlorophenyl)piperazine-d8; NSC 49307-d8; mCPP-d8;
References: Melzacka, M., et al.: Pol. J. Pharmacol Pharm., 32, 551 (1980), Fong, M.H., et al.: J. Pharm. Pharmacol., 34, 674 (1982), Fiorella, D., et al.: Psychopharmacology, 119, 220 (1995), Maes, M., et al.: J. Clin. Psychopharmacol., 17, 358 (1997), Bo Wen, et al.: Drug Metab. Dispos., 36, 841 (2008),

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