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10'-Desmethoxystreptonigrin (10'-Demethoxystreptonigrin)

10'-Desmethoxystreptonigrin (10'-Demethoxystreptonigrin)

Cat no: D3220-89

Supplier: United States Biological
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10'-Desmethoxystreptonigrin is a close analogue of streptonigrin which is produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Catalogue number: D3220-89
Size: 500ug
Purity: >95% by HPLC
Alternative names: 10'-Demethoxystreptonigrin
References: 1. 10'-desmethyloxystreptonigrin, a novel analog of streptonigrin. Liu W.C. et al. J. Antibiot. 1992, 45, 454.

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