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4-1BB LIGAND (TNFSF9, 4-1BBL, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9) (Biotin)

4-1BB LIGAND (TNFSF9, 4-1BBL, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9) (Biotin)

Cat no: 0004-01I

Supplier: United States Biological
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TNFSF9, a type II transmembrane glycoprotein and member of the TNF superfamily, preferentially expressed by B cells, acts as a ligand for CD137 (4-1BB ligand receptor/TNFRSF9). Interaction between 4-1BBL and its receptor acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. Expression of 4-1BBL by a variety of carcinoma cells, suggests a role for 4-1BBL in tumor cell-T cell interactions. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.25-1ug/ml Western Blot: 0.1-0.2ug/ml Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: Streptavidin APC Streptavidin FITC Streptavidin TRITC Streptavidin RPE, RPE Streptavidin HRP Streptavidin Alk. Phos. Storage and Stability: Lyophilized powder may be stored at-20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 0.5ml sterile PBS containing 0.1% BSA. Aliquot and store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 0004-01I
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Conjugates: Biotin
Size: 50ug
Form: Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 0.5ml sterile PBS containing 0.1% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human 4-1BB Ligand (TNFSF9, 4-1BBL, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9)

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