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5-Hydroxy Topotecan Dihydrochloride Salt (Mixture of Diastereomers)

5-Hydroxy Topotecan Dihydrochloride Salt (Mixture of Diastereomers)

Cat no: 161907

Supplier: United States Biological
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Dihydrochloride Salt of 5-Hydroxy Topotecan, is the metabolite of Topotecan (T542500), which is a DNA topoisomerase I inhibitor, semi synthetic analog of Camptothecin, and an antineoplastic. Melting Point: >168 degrees C (dec.) Solubility: DMSO Stability: Hygroscopic Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4 degrees C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive and hygroscopic.
Catalogue number: 161907
Size: 1mg
Form: Supplied as a Orange Solid
Alternative names: (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Dihydrochloride Salt; 10-Hydroxy-9-[(dimethylamino)methyl]-5-hydroxy-(20S,5RS)-camptothecin Dihydrochloride Salt
References: Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990), BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991), Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992),

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