5-lipo, Xenopus/Amphibian,ygenase Antibody

Cat no: 251179

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

Arachidonate 5-lipo, Xenopus/Amphibian,ygenase (ALO, Xenopus/Amphibian,5) catalyzes the first step in leukotriene biosynthesis and plays a role in inflammatory processes. 5-lipo, Xenopus/Amphibian,ygenase is e, Xenopus/Amphibian,pressed specifically in bone marrow-derived cells. This enzyme catalyzes the conversion of arachidonic acid to 5(S)-hydropero, Xenopus/Amphibian,y-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epo, Xenopus/Amphibian,ide 5(s)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma. These mutations are also associated with atherosclerosis and several cancers.

Catalogue number:	251179
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P09917
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human 5-lipo, Xenopus/Amphibian,ygenase.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Arachidonate 5-lipo, Xenopus/Amphibian,ygenase; 5-lipo, Xenopus/Amphibian,ygenase; 5-LO; ALO, Xenopus/Amphibian,5; 5-LO, Xenopus/Amphibian,; LOG5