Home  >  Products  >  a-Dystroglycan (Alpha-Dystroglycan, Alpha-DG, 156DAG, A3a, AGRNR, Cranin, Dystrophin-associated Glycoprotein 1, DAG1, DAG)
a-Dystroglycan (Alpha-Dystroglycan, Alpha-DG, 156DAG, A3a, AGRNR, Cranin, Dystrophin-associated Glycoprotein 1, DAG1, DAG)

a-Dystroglycan (Alpha-Dystroglycan, Alpha-DG, 156DAG, A3a, AGRNR, Cranin, Dystrophin-associated Glycoprotein 1, DAG1, DAG)

Cat no: D9905-04

Supplier: United States Biological
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Cranin is expressed in brain and many other tissues, it binds laminin with high affinity in a calcium dependent manner. It appears to be important in maintaining normal muscle integrity. Loss of cranin from the muscle surface may be one of the primary events leading to muscle injury in congenital muscular dystrophies, it may also play a role in the cognitive deficits often seen in such conditions Applications: Suitable for use in ELISA and Immunohistochemistry. Not suitable for Western Blot. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen): 1:1-1:50 Optimal dilutions to be determined by the researcher. Recommended Positive Control Tissue: Neurons, atsrocytes, smooth muscle, fibroblasts or epithelial cell lines. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9905-04
Reactivities: Human, Mouse, Rat, Chicken/Bird, Sheep, Xenopus/Amphibian
Hosts: Mouse
Applications: ELISA, Immunohistochemistry
Size: 100ul
Form: Supplied as a liquid. No preservatives added.
P type: Mab
Isotype: IgM
Purity: Ascites
Additional info: Recognizes an extracellular region close to the C terminal end of the alpha subunit of human cranin, also known as dystroglycan. Species crossreactivity: mouse, Xenopus, chicken, sheep and rat.

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