a-Fetoprotein, Human (AFP, Alpha1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein precursor, FETA, HPAFP)

AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.\n\nApplications: Suitable for use in ELISA, Western Blot and Inhibition assays. Other applications not tested.\n\nCharacterization:\nOn SDS-PAGE commassie blue stained gel, the purified protein shows a band at 70kD.\n\nStorage and Stability: \nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F4100-19B

Size

2ug

Applications

ELISA, WB

Form

Supplied as a liquid in 0.1M PBS, pH 7.4, 0.1% sodium azide.

Purity

Purified

References

1. Biological aggressiveness of alpha-fetoprotein (AFP)-positive gastric cancer.\n\nHepatogastroenterology 2006 May-Jun;53(69):338-41\n\n2. Hierarchy of {alpha} Fetoprotein (AFP)-Specific T Cell Responses in Subjects with AFP-Positive Hepatocellular Cancer.\n\nJ Immunol 2006 Jul 1;177(1):712-21\n\n3. Rust and Downy Mildew Resistance in Pearl Millet (Pennisetum glaucum) Mediated by Heterologous Expression of the afp Gene from Aspergillus giganteus.\n\nTransgenic Res 2006 Jun;15(3):313-24\n\n4. Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 2005-2006. (Data received in WHO headquarters as of 23 May 2006).\n\nWkly Epidemiol Rec 2006 Jun 9;81(23):234-6\n\n5. [Immunization with dendritic cells infected with human AFP adenovirus vector effectively elicits immunity against mouse hepatocellular carcinomas]\n\nZhonghua Zhong Liu Za Zhi 2006 Jan;28(1):13-6\n\n6. Autosomal recessive ataxia with peripheral neuropathy and elevated AFP: novel mutations in SETX.\n\nNeurology 2006 May 23;66(10):1580-1