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a1-Antichymotrypsin (AACT, Alpha1-ACT)

Cat no: A2298-01D

a1-Antichymotrypsin (AACT, Alpha1-ACT)

Alpha 1-ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.\n\nApplications:\nSuitable for use in ELISA, Inhibition Assays\nand Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOn SDS-PAGE commassie blue stained gel, the purified protein shows a band at 68kD.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

A2298-01D

Size

50ul

Applications

ELISA, WB

Form

Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA, 20% glycerol.

Purity

Purified from human normal serum.

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