Home  >  Products  >  a1-Antichymotrypsin (AACT, Alpha1-ACT, Alpha-1-antichymotrypsin, ACT, Cell Growth-inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, GIG24, GIG25)
a1-Antichymotrypsin (AACT, Alpha1-ACT, Alpha-1-antichymotrypsin, ACT, Cell Growth-inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, GIG24, GIG25)

a1-Antichymotrypsin (AACT, Alpha1-ACT, Alpha-1-antichymotrypsin, ACT, Cell Growth-inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, GIG24, GIG25)

Cat no: A2298-01U

Supplier: United States Biological
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Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Formalin/Paraffin): 1:25-1:50 for 30 minutes at RT. Stains monocytes and macrophages in human tissues and does not stain any other cell type. Optimal dilutions to be determined by the researcher. Positive Control: Tonsil Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A2298-01U
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 500ul
Form: Supplied as a liquid, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified
References: 1. Meis et al. Am J Clin Pathol 86: 591, 1986. 2. Nathrath et al. Acta Histochem 25: 69, 1982.
Additional info: Recognizes human Alpha-1-antichymotrypsin. Species Crossreactivity: most mammals.

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