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a1-Antitrypsin (Serine (or Cysteine) Proteinase Inhibitor, Clade A, Member 1, Protease Inhibitor (alpha-1-Antitrypsin), Protease Inhibitor 1 (anti-Elastase), alpha-1-Antitrypsin, SERPINA1, AAT, PI, A1A, PI1, A1AT, MGC9222, SERPINA1)

Cat no: A2298-02

a1-Antitrypsin (Serine (or Cysteine) Proteinase Inhibitor, Clade A, Member 1, Protease Inhibitor (alpha-1-Antitrypsin), Protease Inhibitor 1 (anti-Elastase), alpha-1-Antitrypsin, SERPINA1, AAT, PI, A1A, PI1, A1AT, MGC9222, SERPINA1)

Alpha 1-ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to alpha-1-ACT. The protein is encoded by a gene (PI) located on the distal long arm of chromosome 14.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500\nOptimal dilutions to be determined by the researcher.\n\nRecommended Secondary Antibodies:\nI1906 IgY, Chicken Pab Rb x Ch \nI1906-10 IgY, Chicken-HRP Rb x Ch \nI1906-12 IgY, Chicken-FITC Rb x Ch \nI1906-14 IgY, Chicken-AP Rb x Ch\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

A2298-02

Size

50ug

Applications

ELISA, WB

Hosts

Ch/Bird

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgY

Additional Info

Recognizes human a1-Antitrypsin. Species Crossreactivity: mouse and rat.

Read more on Supplier website

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

IHC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Ch/Bird

More info

Applications

ICC, IHC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, NHP

More info
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