logo
logo
Advertisehere
MtoZ Horizontal banner
MtoZ Biolabs

Latest promotion FROM:

MtoZ Biolabs
View promotion
A23187

Cat no: A-600

A23187

A23187, Calcimycin, Ca2+ Ionophore A23187, A23187 is a mobile-carrier Ca2+ ionophore (allows Ca2+ ions to cross cell membranes) originally isolated as an antibiotic from Streptomyces chartreusensis. It is used to increase intracellular Ca2+ levels, and for in vitro studies related to intracellular Ca2+ mediated events. A23187 can cause cell activation, differentiation, or proliferation and thus mimics cellular processes observed in response to cytokines and growth factors.

Furthermore, A23187 induces in a concentration and time-dependent manner, Ca2+ triggered cell apoptosis. This property was exploited to clarify apoptotic events in different cell lines such as mouse lymphoma cell line (S49), histiocytic lymphoma U937, human myeloid leukemia cells (HL-60), cultured striatal neurons, renal tubular cells, and C6 glioma cells.
Cell Ca2+ Signaling; Intracellular Ca2+ Mobilizers, Cell Signaling Activators and Inhibitors; Apoptosis Inducers. Cell Ca2+ Signaling; Intracellular Ca2+ Mobilizers. Cell Ca2+ Signaling; Ca2+ Ionophores.

Prices direct from Alomone Labs Ltd.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

A-600

Size

5 mg

Purity

>98%

Concentration

1-10 micro M

Shipping Temp

Room Temperature

Molecular Weight

523.6 da

SUPPLIER INFO

Alomone Labs Ltd.

Latest promotions

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...