AATF Antibody

Cat no: 251597

Supplier: ABBIOTEC

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Description
Additional Information

Protein AATF (AATF) functions as a general inhibitor of the histone deacetylase HDAC1. The binding of AATF to the pocket region of RB1 may displace HDAC1 from RB1/E2F comple, Xenopus/Amphibian,es, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased e, Xenopus/Amphibian,pression of this CDK inhibitor and blocks cell cycle progression. AATF also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer

Catalogue number:	251597
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9NY61
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AATF.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	AATF; Protein AATF; Apoptosis-antagonizing transcription factor; Rb-binding protein Che-1; CHE1; DED