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ABCD4 (ATP-binding Cassette Sub-family D Member 4, PMP70-related Protein, P70R, Peroxisomal Membrane Protein 1-like, PXMP1-L, Peroxisomal Membrane Protein 69, PMP69, PXMP1L)

Cat no: 137512

ABCD4 (ATP-binding Cassette Sub-family D Member 4, PMP70-related Protein, P70R, Peroxisomal Membrane Protein 1-like, PXMP1-L, Peroxisomal Membrane Protein 69, PMP69, PXMP1L)

ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1.25ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137512

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Can

Form

Supplied as a lyophilized powder in PBS. Reconstitute with 100ul dH2O to 1mg/ml.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Additional Info

Recognizes ABCD4. Species Crossreactivity: Human, mouse, rat and canine.

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