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ABCG2 Polyclonal Antibody

Cat no: ABP53289

ABCG2 Polyclonal Antibody

ATP binding cassette subfamily G member 2 (Junior blood group) encoded by ABCG2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

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SPECIFICATIONS

Catalog Number

ABP53289

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum

Gene Id

9429

Isotype

Rabbit IgG

Accession

Q9UNQ0

Clonality

Polyclonal

Concentration

1 mg/ml

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