Abi-1 Antibody

Cat no: 251822

Supplier: ABBIOTEC

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Description
Additional Information

Abelson interactor 1 (Abi-1) negatively regulates cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-1 plays a role in regulation of EGF-induced Erk pathway activation. Abi-1 is involved in cytoskeletal reorganization and EGFR signaling, and together with EPS8 participates in transduction of signals from Ras to Rac. A chromosomal aberration involving Abi-1 is a cause of acute leukemias.

Catalogue number:	251822
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunocytochemistry, Immunohistochemistry
Size:	0.1 mg
Accession:	Q8IZP0
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Abi-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit IgG
Additional info:	Abl interactor 1; Abelson interactor 1; Abi-1; Spectrin SH3 domain-binding protein 1; Eps8 SH3 domain-binding protein; Eps8-binding protein; e3B1; Nap1-binding protein; Nap1BP; Abl-binding protein 4; AblBP4; ABI1; SSH3BP1