ABL1 (7B11) Antibody

Cat no: 252799

Supplier: ABBIOTEC

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Description
Additional Information

c-ABL (Proto-oncogene c-Abl) is a protein kinase that regulates key processes linked to cell growth and survival. c-ABL regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. C-ABL localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. c-ABL regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. A chromosomal aberration involving c-ABL1 is a cause of chronic myeloid leukemia.

Catalogue number:	252799
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P00519
Antigen:	Purified recombinant fragment of ABL1(aa577-650) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	7B11D6
Additional info:	ABL1; Abelson murine leukemia viral oncogene homolog 1; Proto-oncogene tyrosine-protein kinase ABL1; c-ABL; p150; ABL