ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo.
Form:
White Solid
Melting Point:
194-196 degrees C
Solubility:
DMSO, Methanol
Catalogue number:
001028
Size:
10mg
Form:
White Solid
Alternative names:
2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide; A 861695;