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ACADL, NT (ACADL, Long-chain specific acyl-CoA dehydrogenase, mitochondrial)

Cat no: 031519

ACADL, NT (ACADL, Long-chain specific acyl-CoA dehydrogenase, mitochondrial)

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

031519

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Mouse

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)\nMaher, A.C., et al. Mol. Genet. Metab. 100(2):163-167(2010)\nIllig, T., et al. Nat. Genet. 42(2):137-141(2010)\nTalmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)\nLu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)

Additional Info

Mouse

Alternative Names

ACADL, Long-chain specific acyl-CoA dehydrogenase, mitochondrial

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