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Acinus (AAE7, ACN1, AC NON-UTILIZING 1, ACYL-ACTIVATING ENZYME 7, AT3G16910.1, Apoptotic Chromatin condensation inducer in nucleus)

Cat no: A0600-01K

Acinus (AAE7, ACN1, AC NON-UTILIZING 1, ACYL-ACTIVATING ENZYME 7, AT3G16910.1, Apoptotic Chromatin condensation inducer in nucleus)

Apoptotic events such as chromatin condensation and nuclear fragmentation are triggered by the activation of a family of cysteine proteases called caspases. A novel protein, Acinus, indices apoptotic chromatin condensation after cleavage by caspase-3 without inducing DNA fragmentation and is essential for apoptotic chromatin condensation.\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500-1:1,000. \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

A0600-01K

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

PBS with 0.02% sodium azide

P Type

Pab

Purity

Purified

References

1. Sahara, S., et al. Nature. Sept.9; 401(6749) : 168-173 (1999)

Additional Info

Reacts with the C-terminus of Acinus. Species Crossreactivity: Human. Other species have not been tested.

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