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Acinus (AAE7, ACN1, AC NON-UTILIZING 1, ACYL-ACTIVATING ENZYME 7, AT3G16910.1, Apoptotic Chromatin condensation inducer in nucleus)

Cat no: A0600-05

Acinus (AAE7, ACN1, AC NON-UTILIZING 1, ACYL-ACTIVATING ENZYME 7, AT3G16910.1, Apoptotic Chromatin condensation inducer in nucleus)

Apoptotic events such as chromatin condensation and nuclear fragmentation are triggered by the activation of a family of cysteine proteases called caspases.A novel protein, Acinus, induces apoptotic chromatin condensation after cleavage by caspase-3 without inducing DNA fragmentation and is essential for apoptotic chromatin condensation.\n\nApplications:\nWestern Blot: Use at 1:500 to 1:1000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degrees C or colder. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

A0600-05

Size

100ug

Applications

ELISA, WB

Hosts

Rabbit

Form

Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.

P Type

Pab

Purity

Purified IgG

Isotype

IgG

References

1. Sahara S. et al. Nature 1999 Sep 9;401(6749):168-73.

Additional Info

Reacts with the N-terminus of Acinus.

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