ACOT2 (T209) Peptide

Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT1 (acyl-CoA thioesterase 1, also known as CTE1) and ACOT2 (acyl-CoA thioesterase 2, also known as PTE2) are members of the ACOT family and exhibit different cellular localization, with ACOT1 existing as a monomer in the cytoplasm and ACOT2 localized primarily to mitochondria. Characteristic of most ACOT proteins, ACOT1 and ACOT2 catalyze the conversion of Palmitoyl-CoA and water to free CoA and palmitate, a reaction that is important for the regulation of intercellular fatty acid levels. ACOT2 is expressed as multiple alternatively spliced isoforms and, like ACOT1, is encoded by a gene which maps to human chromosome 14.

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SPECIFICATIONS

Catalog Number

BS3060P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide ACOT2 (T209). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P49753

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3060 ACOT2 (T209) pAb.

Alternative Names

ACOT2; Acyl CoA thioesterase 2; Acyl coenzyme A thioester hydrolase 2a; Acyl coenzyme A thioesterase 2; mitochondrial; CTE Ia; CTE1A; Long chain acyl CoA thioesterase 2; Mitochondrial acyl CoA thioesterase 1; Mitochondrial acyl CoA thioesterase 2; MTE1; Peroxisomal long chain acyl coA; PTE2; PTE2A; ZAP128;