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Acrp30 (Adipocyte Complement-related Protein of 30kD, Adiponectin, AdipoQ, apM1, Gelatin Binding Protein 28, GPB28)

Acrp30 (Adipocyte Complement-related Protein of 30kD, Adiponectin, AdipoQ, apM1, Gelatin Binding Protein 28, GPB28)

Cat no: A0891-01A

Supplier: United States Biological
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Adiponectin, (also known as Acrp30) is a 244 amino acid major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice. Matched Pair: Capture: A0891-01B Detection: A0891-01A Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A0891-01A
Reactivities: Human
Hosts: Mouse
Applications: ELISA
Size: 200ug
Form: Supplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein A chromatography.
References: 1. Lihn, A.S. et al. (2005) Adiponectin: action, regulation and association to insulin sensitivity. Obes. Rev. 6: 13-21. 2. Trayhurn, P. and Wood, I.S. (2005) Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem. Soc. Trans. 33: 1078-1081.
Additional info: Recognizes human adiponectin.

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