Actin, alpha (ACTA1, ACTA, skeletal muscle, Alpha-actin-1) (FITC)

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA.\n\nRecommended Dilution:\nELISA: 1:1000\nWestern Blot: 1:100~500\nImmunohistochemistry: 1:10~50\nFlow Cytometry 1:10~50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

030740-FITC

Size

100ul

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1,k

References

Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010)\nHaigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010)\nYu, G., et al. J Clin Neurosci 17(6):766-769(2010)\nYu, C.H., et al. PLoS ONE 5 (7), E11878 (2010)\nLicastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)

Additional Info

Human

Alternative Names

ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1