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Actinin-alpha1/2/3/4 (W48) Peptide

Actinin-alpha1/2/3/4 (W48) Peptide

Cat no: BS2206P

Supplier: Bioworld Technology, Inc.
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The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and alpha-actinins. There are four tissue-specific alpha-actinins, namely alpha-actinin-1, alpha-actinin-2, alpha-actinin-3 and alpha-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each alpha-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding alpha-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure.
Catalogue number: BS2206P
Applications: Block/Neutralize/Inhibit
Swiss prot: P12814/P35609/Q08043/O43707
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Actinin-alpha1/2/3/4 (W48). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: pan-alpha-Actinin; alpha-Actinin-pan; Actinin-alpha; Actinin alpha; alpha Actinin; alpha-Actinin; Alpha-actinin-4; F-actin cross-linking protein; Non-muscle alpha-actinin 4; ACTN4; alpha-Actinin4; Actinin alpha4; Actininalpha4; alphaActinin-4; Actinin-alpha4; alpha-actinin-4; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; Non-muscle alpha-actinin-1; ACTN1; alpha-Actinin1; Actinin alpha1; Actininalpha1; alphaActinin-1; Actinin-alpha1; alpha-actinin-1; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; ACTN2; alpha-Actinin2; Actinin alpha2; Actininalpha2; alphaActinin-2; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; ACTN3; alpha-Actinin3; Actinin alpha3; Actininalpha3; alphaActinin-3; Actinin-alpha3; alpha-actinin-2; alpha-actinin-3
Additional info: This peptide can be used with studies using BS2206 Actinin-alpha1/2/3/4 (W48) pAb.

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