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Actinopyrone A

Cat no: A0853


Supplier: United States Biological
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Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp.. It shows selective (>10e6 fold) and potent (MIC 0.0001 ug/ml) activity against Helicobacter pylori, the principle cause of peptic ulcer disease. Actinopyrone A was originally identified for its coronary vasodilating activity and weak activity against some Gram-positive bacteria and dermatophytes. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO Related to: Piericidin A
Catalogue number: A0853
Size: 500ug
Purity: >95% by HPLC
References: 1. -Pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M. et al. J. Antibiot. 2000, 53, 844. 2. Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties. Yano K. et al. J. Antibiot. 1986, 39, 32. 3. Actinopyrones A, B and C, new physiologically active substances. II. Physico-chemical properties and chemical structures. Yano K. et al. J. Antibiot. 1986, 39, 38.

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