Home  >  Products  >  Activator of 90kD Heat Shock Protein ATPase Homolog 1 (Activator of Heat Shock 90kDa Protein ATPase Homolog 1, AHA1, AHSA1, C14orf3, HSPC322, p38) (Azide Free)
Activator of 90kD Heat Shock Protein ATPase Homolog 1 (Activator of Heat Shock 90kDa Protein ATPase Homolog 1, AHA1, AHSA1, C14orf3, HSPC322, p38) (Azide Free)

Activator of 90kD Heat Shock Protein ATPase Homolog 1 (Activator of Heat Shock 90kDa Protein ATPase Homolog 1, AHA1, AHSA1, C14orf3, HSPC322, p38) (Azide Free)

Cat no: A0855-77

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4). Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot:0.5-1:1000 Immunoprecipitation:1:10000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0855-77
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1. Hainzl O., Lapina M.C., Buchner J., Richter K. (2009) J Biol Chem. Epub. 2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387(pt.3):789-796. 3. Lotz G.P., Brychzy A., Heinz S., Obermann W.M. (2008) J Cell Sci. 121(pt.5):717-723. 4. Holmes J.L., Sharp S.Y., Hobbs S., Workman P. (2008) Cancer Res. 68(4): 1188-1197.
Additional info: Recognizes mouse Aha1. Species Crossreactivity: human, rat,

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave