ACTR-IIB Antibody

Cat no: 251300

Supplier: ABBIOTEC

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Description
Additional Information

Activin receptor type-2B (ACTR-IIB), upon ligand binding, forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Defects in ACTR-IIB are the cause of visceral heterota, Xenopus/Amphibian,y autosomal type 4 (HT, Xenopus/Amphibian,4), a form of visceral heterota, Xenopus/Amphibian,y, a comple, Xenopus/Amphibian, disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. HT, Xenopus/Amphibian,4 results in an abnormal arrangement of visceral organs and a wide variety of congenital defects.

Catalogue number:	251300
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q13705
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ACTR-IIB.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Activin receptor type-2B; Activin receptor 2B; Activin receptor type IIB; ACTR-IIB; ACVR2B