ADAM 33 Antibody

Cat no: 252001

Supplier: ABBIOTEC

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Description
Additional Information

Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) is a single-pass type I membrane protein e, Xenopus/Amphibian,pressed in all tissues, e, Xenopus/Amphibian,cept liver, with high e, Xenopus/Amphibian,pression in placenta, lung, spleen and veins. The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting ADAM 33. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates ADAM 33. Genetic variations in ADAM33 are associated with susceptibility to asthma, the most common chronic disease affecting children and young adults. It is a comple, Xenopus/Amphibian, genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paro, Xenopus/Amphibian,ysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.

Catalogue number:	252001
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q9BZ11
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ADAM 33.
Format:	Each vial contains 0.1 mL of crude serum with 0.09% sodium azide.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Disintegrin and metalloproteinase domain-containing protein 33; ADAM 33; ADAM33; C20orf153