ADAM-TS7 Antibody

Cat no: 250456

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS7) is a metalloprotease that degrades COMP. ADAM-TS7 is up-regulated in articular cartilage and synovium from arthritis patients. The spacer domain and the thrombospondin type-1 domain are important for a tight interaction with the e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian,. The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.

Catalogue number:	250456
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9UKP4
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ADAM-TS7.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAMTS-7; ADAM-TS 7; ADAM-TS7; COMPase; ADAMTS7