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ADAM8 (Disintegrin and Metalloproteinase Domain-containing Protein 8, ADAM 8, Cell Surface Antigen MS2, CD156a, MS2)

ADAM8 (Disintegrin and Metalloproteinase Domain-containing Protein 8, ADAM 8, Cell Surface Antigen MS2, CD156a, MS2)

Cat no: A0858-98P

Supplier: United States Biological
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Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant aa sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:3000 Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0858-98P
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ul
Form: Supplied as a liquid in PBS, pH 7.0, 1% BSA, 0.01% thimerosal, 20% glycerol.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human ADAM8.

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