ADAMTS-4 is a glutamyl endopeptidase that cleaves aggrecan and brevican. The degradation of aggrecan, a cartilage proteoglycan, has been linked to rheumatoid arthritis, osteoarthritis, retinal diseases, Alzheimers disease and other neurodegenerative diseases.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.