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Adducin ?/? Polyclonal Antibody

Cat no: ABP50605

Adducin ?/? Polyclonal Antibody

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

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SPECIFICATIONS

Catalog Number

ABP50605

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

118/119

Isotype

Rabbit IgG

Accession

P35611/P35612

Clonality

Polyclonal

Concentration

1 mg/ml

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