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Adenosine A2a Receptor (A2aR)

Cat no: A0869-56A


Supplier: United States Biological
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This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8,000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A0869-56A
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: ADORA2A, HGNC:263, RDC8, hA2aR, Adenosine Receptor Subtype A2a
References: Retey JV, Adam M, Honegger E, Khatami R, Luhmann UF, Jung HH, Berger W, Landolt HP. . A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans.. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15676-81. Epub 2005 Oct 12. . PMID: 16221767
Additional info: Species Crossreactivity: Expected crossreactivity based upon sequence homology: Human

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