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Adenosine Deaminase, RNA-specific, B1 (ADARB1, ADAR2, Double-stranded RNA-specific Editase 1, DRABA2, DRADA2, dsRNA Adenosine Deaminase, RNA Editase, RNA-editing Deaminase 1, RED1, RNA-editing Enzyme 1)

Cat no: A0870-20W

Adenosine Deaminase, RNA-specific, B1 (ADARB1, ADAR2, Double-stranded RNA-specific Editase 1, DRABA2, DRADA2, dsRNA Adenosine Deaminase, RNA Editase, RNA-editing Deaminase 1, RED1, RNA-editing Enzyme 1)

The mammalian Adenosine Deaminases Acting on RNA (ADAR) constitute a family of sequence-related proteins involved in pre-mRNA editing of nuclear transcripts through site-speci?c adenosine modi?cation. ADARs are not active on adenosine-mononucleotide and are only distantly related by sequence to adenosine and AMP deaminases involved in purine metabolism. The ADARs convert certain adenosine bases in an RNA transcript into inosines by removing an amino group involved in Watson-Crick base pairing. The ADARs recognize a double stranded RNA (dsRNA) structure in the transcript that is formed between the editing site complementary sequence (ECS), usually located in the downstream 3

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SPECIFICATIONS

Catalog Number

A0870-20W

Size

50ug

Applications

WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human ADARB1.

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